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Lait de chamelle en poudre – 1OOg . Cure de 10 jours, bénéfique pour votre immunité mais aussi pour les grossesses, problèmes digestifs et diabète

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Camel milk and lactoferrin

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Camel milk has a high level of lactoferrin, but do you know what lactoferrin is?

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Lactoferrin is a glycoprotein from the transferrin family that binds to iron and plays many biological roles. It has antibacterial, antiviral, antifungal, anti-inflammatory, antioxidant and immunomodulatory properties . Groves, in 1960, isolated lactoferrin from cow’s milk for the first time. This molecule is present in colostrum, the milk of the young mother just after childbirth. It was in 1966 that the presence of lactoferrin was demonstrated in saliva, nasal secretions, tears, bile, pancreatic fluid, semen, cervical mucus in women and in urine .

It belongs to the family of transferrin proteins. Structurally, lactoferrin is an 80 kDa glycoprotein.

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Antioxidant virtues

Upon activation of the immune system, the activation of immune cells such as monocytes and macrophages leads to increased production of free radicals which can be amplified in the presence of free iron. Due to its strong affinity with free iron, lactoferrin released at the site of inflammation by immune cells (neutrophils) traps iron. Lactoferrin works as a powerful local antioxidant protecting immune cells from free radicals generated during the inflammatory response. Recently, a clinical study on a cohort of 90 patients with chronic hepatitis C shows that subjects who ingested lactoferrin show an improvement in their hepatic oxidative status.

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Immunomodulatory action

The immunomodulatory actions of lactoferrin on the immune system are not clearly understood. However, it strengthens the immune response by the presence of specific lactoferrin receptors located on many immune cells, such as lymphocytes, monocytes and macrophages. It is directly involved in the regulation of the activity of natural killer cells (NK).

Published scientific studies that examined the use of lactoferrin as a supplement and its effects on immunity are very promising: two studies in healthy volunteers showed that ingestion of lactoferrin from cow’s milk had adverse effects. positive immunoregulatory effects depending on the initial profile of the volunteer immune system. The results suggest that lactoferrin from cow’s milk could be used clinically to improve the immune status of patients and thus could act on the activation of the patient’s defense system.

The immunomodulatory actions of this molecule on the immune system are not clearly understood. However, lactoferrin strengthens the immune response by the presence of specific lactoferrin receptors located on many immune cells, such as lymphocytes, monocytes and macrophages. It is directly involved in the regulation of the activity of natural killer cells (NK). Published scientific studies that examined the use of lactoferrin as a supplement and its effects on immunity show great promise: Two studies in healthy volunteers showed that ingestion of lactoferrin from cow’s milk had positive immunoregulatory effects. depending on the initial profile of the volunteer immune system. The results suggest that lactoferrin from cow’s milk could be used clinically to improve the immune status of patients and thus could act on the activation of the patient’s defense system.

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Cancer

Tumor suppressor genes lose their function in cancers, and the expression of the lactoferrin gene has been shown to be greatly reduced or even extinguished in some cancers. Alterations inactivate the lactoferrin gene providing cancer cells with a proliferative advantage 9 . By performing a role of monitoring cell growth , it fights against the development of metastases, suggesting that this molecule could play the role of a tumor suppressor 10 11 12 . Numerous in vitro and in vivo animal research suggests that lactoferrin is a potent anticancer agent. Multiple studies in rats or mice exposed to toxic chemicals (azoxymethane) known to cause tumors show a significant reduction in the development of adenocarcinomas in animals given lactoferrin.

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Intestinal system

The benefits of lactoferrin also have a strong impact on the health of the intestinal system.
Lactoferrin appears to be involved in the proper functioning of the intestine. Indeed, studies suggest that it significantly reduces intestinal inflammation, in conditions such as inflammatory bowel disease. Animals exposed to various pathogens known to cause intestinal inflammation show decreased inflammation when fed lactoferrin.

Dysbiosis of the gut microbiota (an imbalance between good and bad bacteria) is known to induce an inflammatory state of the gut resulting in disturbances throughout the body. Scientific research has shown that lactoferrin intake in animals or infants causes a very significant increase in the number of good bacteria – such as bifidus – and a decrease in bad bacteria such as E. coli, Streptococcus, Clostridium and others. Maintaining the balance of the gut microbiota. Finally,
some studies suggest that lactoferrin is able to stimulate the proliferation of intestinal cells, leading to improved digestive functions.

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Anti-microbial activity

Lactoferrin has anti-inflammatory benefits . It exerts an anti-infectious activity against many micro-organisms such as Gram- and Gram + bacteria, yeasts, fungi, some viruses and protozoa . Further research has shown that the expression of lactoferrin may be induced by LPS, a proinflammatory agent.

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Anti-bacterial activity

Lactoferrin has antibacterial activity . A clinical trial investigated the effect of antibiotic treatment alone or in combination with 200 mg lactoferrin in 150 patients with Helicobacter pylori infection. The results showed 100% eradication of Helicobacter pylori in the group that received lactoferrin. In the one receiving conventional treatment, the level of eradication was 76.9% 24 . In another study, 12 children with chronic pharyngitis who tested positive for group A streptococci were given a combination of 500 mg erythromycin and 100 mg bovine lactoferrin three times daily. After fifteen days of treatment, the results show a greater decrease in intracellular group A streptococci in children who received the antibiotic treatment combined with lactoferrin.

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Antiviral activity

Lactoferrin directly kills certain viruses by binding to viral receptor sites, preventing viruses from infecting healthy cells. Also acting indirectly, lactoferrin inhibits viruses by increasing the immune response to viral invasion.

One study looked at patients with HIV infection and compared them to healthy volunteers. The results showed that plasma lactoferrin levels were lower in patients with HIV . Another study was performed on 11 patients with chronic hepatitis C to measure the effectiveness of different doses of lactoferrin (daily for eight weeks) on reducing the viral load. The results showed that lactoferrin significantly lowered viral load, with decreases of up to 50% in four patients . Early clinical trials have shown that oral administration of lactoferrin increased viral load reduction in herpesvirus infected patients treated with acyclovir.

Lactoferrin directly kills certain viruses by binding to viral receptor sites, preventing viruses from infecting healthy cells. Also acting indirectly, lactoferrin inhibits viruses by increasing the immune response to viral invasion. One study looked at patients infected with HIV and compared them to healthy volunteers. The results showed that plasma lactoferrin levels were lower in patients infected with HIV .

Another study was performed on 11 patients with chronic hepatitis C to measure the effectiveness of different doses of lactoferrin (daily for eight weeks) on reducing the viral load. The results showed that lactoferrin significantly lowered viral load, with decreases of up to 50% in four patients . Early clinical trials have shown that oral administration of lactoferrin increased viral load reduction in herpesvirus infected patients treated with acyclovir.

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Regulation of iron absorption

Lactoferrin is essential because of its amazing ability to bind with iron . Iron is used by many pathogens and tumors to grow. By binding to iron, lactoferrin deprives them of this resource while facilitating absorption of this mineral by the intestine.

Source: doctonat.com